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Abstract #5016

Comparison of cardiac output calculated from low dose Ultra-fast DCE MRI to the values measured from cardiac MRI

Shiyang Wang1, Yue Zhang1, Xiaobing Fan1, Dianning He1, Milica Medved1, Tatjana Antic2, Ambereen Yousuf1, Gregory Karczmar1, and Aytekin Oto1

1Radiology, University of Chicago, Chicago, IL, United States, 2Pathology, University of Chicago, Chicago, IL, United States

Accurately measuring arterial input function (AIF) is essential for quantitative dynamic contrast enhanced (DCE) MRI. The indicator dilution principle was used to verify the accuracy of AIF measured at iliac arties following injection of low dose (0.015 mmol/kg) gadolinium contrast media. The cardiac output from cardiac MRI (COCMRI) were compared with the cardiac output from Ultra-fast DCE-MRI (CODCE). Results demonstrated that the CODCE were consistent with the ‘gold standard’ COCMRI. This demonstrates that the low dose ultra-fast DCE-MRI can be used to accurately measure the AIF.

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