Abstract #5022

Investigating the nature of distinct regions in brain tissue affected by stroke with principal component analysis of multi-b valued diffusion data

Ana-Maria Oros-Peusquens¹, Omid Nikoubashman², Martin Wiesmann², and N. Jon Shah¹

¹Institute of Neuroscience and Medicine 4, Medical Imaging Physics, Research Centre Juelich, Juelich, Germany, ²Department of Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany

A data-driven, observer-independent segmentation of brain regions affected by stroke is proposed. It is based on PCA analysis of a multi b-value diffusion trace acquisition and offers fast, high-SNR visualisation of affected areas. Substructure of these areas is easily identified and can be automatically delineated using clustering algorithms.

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