Meeting Banner
Abstract #5027

Performance of ultrafast DCE-MRI for diagnosis of prostate cancer

Aritrick Chatterjee1, Dianning He1,2, Xiaobing Fan1, Shiyang Wang1, Teodora Szasz3, Ambereen Yousuf1, Federico Pineda1, Tatjana Antic4, Melvy Mathew1, Gregory S Karczmar1, and Aytekin Oto1

1Department of Radiology, University of Chicago, Chicago, IL, United States, 2Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Shenyang, China, 3Research Computing Center, University of Chicago, Chicago, IL, United States, 4Department of Pathology, University of Chicago, Chicago, IL, United States

This study aimed to test high temporal resolution DCE- MRI for different zones of the prostate and evaluate its performance in the diagnosis of prostate cancer (PCa). High temporal resolution (~2.2s) was achieved by modestly decreasing spatial resolution, increasing sensitivity encoding and partial Fourier factors. Our results show that PCa had significantly faster signal enhancement and washout rates than normal tissue. DCE-MRI with higher temporal resolution may capture clinically useful information for PCa diagnosis that would be missed by low temporal resolution DCE-MRI. This new information could improve the performance of mpMRI in prostate cancer detection.

This abstract and the presentation materials are available to members only; a login is required.

Join Here