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Abstract #5052

Ultra-high-field (7 Tesla) MRI study of the articular cartilage in normal subjects

Giacomo Aringhieri1, Massimo Marletta1, Sara Toscano1, Laura Biagi2, Gianluigi Tiberi2, Michela Tosetti2, Mirco Cosottini3, and Virna Zampa4

1Radiology, University of Pisa, Pisa, Italy, 2Imago 7 foundation, Pisa, Italy, 3Neuroradiology, University of Pisa, Pisa, Italy, 4Radiology, University Hospital of Pisa, Pisa, Italy

Ultra High Field MRI gives the opportunity to study in vivo articular cartilage with optimal signal-to-noise ratio, contrast-to-noise ratio and spatial resolution in comparison with lower field strength systems. We obtained the mean T2 and T2* maps values for under and over 50 years aged healthy subjects, both mean values increase with the subjects' age. With dedicated multichannel coils and specific cartilage sequences, it is possible to make both a qualitative and a quantitative evaluation of early and pre-clinical cartilage ageing-related changes in estimating the water content and the integrity of the cartilage matrix.

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