Abstract #5065

Effectiveness of fatty fraction by high-speed T2-corrected multi-echo SVS (HISTO) and multi-echo 3D DIXON (mDIXON) in rapid and robust acquisition for Duchenne Muscular Dystrophy

Xiaolei Zhu¹, Guijin Li², and Zhiyong Li³

¹MR SMK, Siemens Healthcare, NE Asia, Guangzhou, China, ²CS App, Siemens healthcare, NE Asia, Guangzhou, China, ³Department of Radiology, Shenzhen Children Hospital, Shenzhen, China

The purpose of this study is to assess a potential fat quantitative technique in Duchenne muscular dystrophy (DMD), one of High-Speed T2-corrected multi echo (HISTO) acquisition with multi echo MRS, which is a rapid way in quantifying fatty content of pelvic and thigh muscles with confound effect, and then a rapid multi echo 3D Dixon technique was performed with multi peak fitted and R2* correction method to further evaluated the un-confounded fat fraction and the region of fat content in muscles. Proposed protocol was used to quantify the accuracy of fat fraction in DMD patients; both of measurements demonstrate strong consistency in fat quantification.

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