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Abstract #5065

Effectiveness of fatty fraction by high-speed T2-corrected multi-echo SVS (HISTO) and multi-echo 3D DIXON (mDIXON) in rapid and robust acquisition for Duchenne Muscular Dystrophy

Xiaolei Zhu1, Guijin Li2, and Zhiyong Li3

1MR SMK, Siemens Healthcare, NE Asia, Guangzhou, China, 2CS App, Siemens healthcare, NE Asia, Guangzhou, China, 3Department of Radiology, Shenzhen Children Hospital, Shenzhen, China

The purpose of this study is to assess a potential fat quantitative technique in Duchenne muscular dystrophy (DMD), one of High-Speed T2-corrected multi echo (HISTO) acquisition with multi echo MRS, which is a rapid way in quantifying fatty content of pelvic and thigh muscles with confound effect, and then a rapid multi echo 3D Dixon technique was performed with multi peak fitted and R2* correction method to further evaluated the un-confounded fat fraction and the region of fat content in muscles. Proposed protocol was used to quantify the accuracy of fat fraction in DMD patients; both of measurements demonstrate strong consistency in fat quantification.

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