Abstract #5064

Modeling skeletal muscle perfusion through application of the continuous time random walk model to diffusion-weighted images

David Reiter^1,2, Fatemeh Adelnia², Donnie Cameron³, Christopher Bergeron², Richard G. Spencer², and Luigi Ferrucci²

¹Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, ²National Institute on Aging, Baltimore, MD, United States, ³Clinical Magnetic Resonance Physics, University of East Anglia, Norwich, United Kingdom

The continuous time random walk (CTRW) model provides a flexible framework for representing complex diffusive processes, allowing for smooth interpolation between sub- and super-diffusion. This work presents supporting arguments for the application of the CTRW model to the measurement of skeletal muscle perfusion. We present model fit parameters from DW images of human skeletal muscle and compare estimates of intravascular volume fraction with previously reported values obtained using intravital microscopy.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.