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Abstract #5106

Chemical Exchange Rotation Transfer imaging of Phosphocreatine in Muscle

Zhongliang Zu1, Eugene C Lin1, Elizabeth A Louie1, Xiaoyu Jiang1, Christopher L Lankford1, Bruce M Damon1, Mark D Does1, John C Gore1, and Daniel F Gochberg1

1Radiology Department, Vanderbilt University, Nashville, TN, United States

CEST imaging of Creatine has been reported, whereas selective mapping of PCr in vivo has not been implemented. We found that CEST imaging of Creatine may be influenced by other molecules in muscle, but CERT imaging of PCr is more specific and thus should be a better indicator of changes of flux through the CK reaction.

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