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Abstract #5107

Chemical Exchange Saturation Transfer imaging of prostate cancer at 3T: Repeatability, and initial results of an acquisition and multi-pool analysis protocol

Vincent Evans1, Francisco Torrealdea1, Marilena Rega2, Mina Kim3, Mrishta Brizmohun Appayya1, Arash Latifoltojar1, Shonit Punwani1, Xavier Golay3, and David Atkinson1

1Centre for Medical Imaging, UCL, London, United Kingdom, 2Institute of Nuclear Medicine, UCLH, London, United Kingdom, 3Brain Repair and Rehabilitation, Institute of Neurology, UCL, London, United Kingdom

An optimised acquisition and post-processing protocol for multi-pool Lorentzian analysis of CEST data in the prostate at 3T is described. The repeatability of the technique is evaluated in five healthy volunteers and the contrast observed between healthy tissue, TZ tumour and PZ tumour in two prostate cancer patients is evaluated.

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