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Abstract #5191

High resolution 1 mm isotropic semi continuous wave gagCEST of articular cartilage using parallel transmit at 7T

Sander Brinkhof1, Vitaliy Khlebnikov1, Fredy Visser1,2, and Hans Hoogduin1

1Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2Philips Healthcare, Best, Netherlands

The purpose of this work was to implement gagCEST imaging in articular cartilage at 7T using a parallel transmit setup. Two alternating sets of four transmit channels were used in quadrature mode to create a semi continuous excitation pulse. Using this setup, an isotropic 1 mm spatial resolution could be achieved with a low coefficient of variation of 1.05% (@0.9ppm) within an acquisition time of 5 minutes. To the best of our knowledge, this is the highest gagCEST resolution shown so far in literature.

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