Abstract #5205

Exploring peritumoral neural tracts by using Neurite Orientation Dispersion and Density Imaging

Shin Tai Chong¹, Hung-Wen Kao², Chien-Yuan Eddy Lin³, Chiao-Chi Chen⁴, Chun-Yi Zac Lo⁵, Ching-Po Lin¹, and Chen Chang⁴

¹Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, ²Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ³GE Healthcare MR Research China, Beijing, China, People's Republic of, Taipei, Taiwan, ⁴Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, ⁵Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China

We hypothesized that the Neurite Orientation Dispersion and Density Imaging (NODDI)-based tractography could improve the reconstruction of the fiber tracts that by tracking through regions of peritumoral edema. In visual comparison with diffusion tensor imaging (DTI), this model provided similar performance in healthy side and better performance in the corticospinal tract (CST) of the affected side. This technique may help neurosurgeons to define an optimal safe margin for total resection.

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