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Abstract #5206

The impact of structure tensor informed fibre tractography (STIFT) on structural connectivity

Kwok-Shing Chan1, David G. Norris1, and José P. Marques1

1Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Structure tensor informed fibre tractography(STIFT) incorporating white matter morphology from gradient echo data to diffusion data is beneficial in the presence of kissing and highly curved fibres. However, previous demonstrations of STIFT provide only qualitative results and its performance beyond the initial targets (optic radiation and cingulum) is still unknown. This study investigated the quantitative effects of STIFT through structural connectivity comparison between diffusion tractography and STIFT. We found that there is no change of connectivity with STIFT in major structural connections.

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