Meeting Banner
Abstract #5304

Whole brain effect of real-time fMRI amygdala neurofeedback emotional training and its association with PTSD symptom reduction

Masaya Misaki1, Vadim Zotev1, Raquel Phillips1, Chung-Ki Wong1, Brent Wurfel1,2, Frank Krueger3, Matthew Feldner4, and Jerzy Bodurka1,5

1Laureate Institute for Brain Research, Tulsa, OK, United States, 2Laureate Psychiatric Clinic and Hospital, Tulsa, OK, United States, 3George Mason University, Fairfax, VA, United States, 4University of Arkansas, Fayetteville, AR, United States, 5University of Oklahoma, Norman, OK, United States

The effect of real-time fMRI neurofeedback (rtfMRI-nf) training with the left amygdala activity on whole brain regions and their association with symptom reduction was investigated in veterans with combat-related PTSD. The main effect of training was seen in the salience network regions including anterior insula and the anterior cingulate cortex (ACC). The decrease in ACC response was significantly correlated with a decrease in PTSD symptoms. These results indicated that the effect of rtfMRI-nf training was not limited to the left amygdala but other emotion-related regions were co-modulated during the training. The treatment response could be meditated by those regions.

This abstract and the presentation materials are available to members only; a login is required.

Join Here