Abstract #5321

Multiband Diffusion-Weighted MRI of the Eye and Orbit Free of Geometric Distortions Using a RARE-EPI Hybrid

Katharina Paul¹, Till Huelnhagen¹, Sebastian Schmitter², Oliver Stachs³, and Thoralf Niendorf^1,4

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, ³Department of Ophthalmology, University of Rostock, Rostock, Germany, ⁴Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

This study shows that multiband diffusion-weighted RARE-EPI has the capability to acquire distortion-free images of the eye and orbit with ample diffusion contrast for slices in close proximity. The results underpin the challenges of ocular imaging at 3.0 T and 7.0 T for echo planar imaging and demonstrate that these issues can be offset by using accelerated RARE based approaches. This benefit can be exploited for the assessment of spatial arrangements of the eye segments and their masses with the goal to provide guidance in diagnostic assessment and treatment of ophthalmological diseases.

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