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Abstract #5323

Diffusion-weighted MRI of the prostate without susceptibility artifacts: Multi-shot STEAM with radial undersampling

Andreas Merrem1, Klaus-Dietmar Merboldt1, Jakob Klosowski1, and Jens Frahm1

1Biomedizinische NMR Forschungs GmbH, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

Undersampled radial STEAM MRI allows for diffusion-weighed imaging without susceptibility artifacts. Here, this technique was developed for applications to the prostate by moving to a multi-shot acquisition and reconstruction method to optimally process data with limited SNR. Numerical simulations defined the conditions for accurate ADC measurements. In vivo studies of healthy subjects resulted in ADC values in the central gland of the prostate which are consistent and in agreement with previous literature values. A comparison of DW STEAM and DW EPI of the prostate confirmed the major benefit of STEAM sequences which are free of susceptibility-induced distortions.

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