Diffusion weighted imaging such as intravoxel incoherent motion (IVIM) and non-Gaussian diffusion (NG-diff) allow the non-invasive study of tissue perfusion and are able to infer the organisation of the microstructure, respectively. Both are highly relevant in pathology characterisation, but are often acquired separately. Here we propose a unified IVIM/NG-diff protocol and apply it to brain tumour patients undergoing preoperative or follow-up scans in a hybrid MR-PET environment. The results agree well with previously reported values using standard techniques. Furthermore, indication for tumour grading power of IVIM parameters was found.
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