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Abstract #5357

Intravoxel Incoherent Motion Imaging of Thermoregulation in Skeletal Muscle

Kemal Sümser1, Juan Antonio Hernandez-Tamames2, Gerard Cornelis van Rhoon1, and Margarethus Marius Paulides1

1Radiation Oncology, Erasmus Medical Center, Rotterdam, Netherlands, 2Radiology Department, Erasmus Medical Center, Rotterdam, Netherlands

Accurate temperature dependent perfusion maps are needed for accurate thermal modelling. In this study, perfusion maps were created for human leg muscle at rest and under cold stress using Intravoxel Incoherent Motion (IVIM) Diffusion Weighted Imaging. IVIM parameters decreasesignificantly under cold stress. Consistency of inter-subject measurements proved IVIM method is suitable for imaging temperature dependent perfusion maps.

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