Meeting Banner
Abstract #5368

Longitudinal Changes in Gray Matter Regions after Cranial Radiation and Comparative Analysis with Whole Body Radiation: A DTI Study

Poonam Rana1, Apurva Watve1, Mamta Gupta1, Richa Trivedi1, and Subash Khushu1

1NMR Research Centre, Institute of Nuclear Medicine and Allied Sciences, Delhi, India

Radiation induced white matter changes are well known and vastly studied. However, radiation induced gray matter alterations are still a research question. In the present study, DTI based gray matter changes in C57BL/6 mice were studied following cranial and whole body irradiation at 5 Gy during sub acute and early delayed time point. Longitudinal changes in FA and MD were observed till 8 months post radiation. Comparative analysis depicted differential response after cranial and whole body radiation exposure with prominent alterations in cranially irradiated animals. with most changes at 8 months post irradiation

This abstract and the presentation materials are available to members only; a login is required.

Join Here