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Abstract #5393

Investigating the value of arterial spin labeling (ASL) and intravoxel incoherent motion (IVIM) imaging on the diagnosis of nasopharyngeal carcinoma (NPC) in T1 stage

Meng Lin1, Xiaoduo Yu1, and Lizhi xie2

1National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2GE Healthcare, MR Research China, Beijing, China

T1-stage NPC was difficult to diagnosis using conventional MRI and additional examinations were often needed. This study aimed to investigate ASL and IVIM on diagnosing T1-stage NPC. We measured the BF by ASL and IVIM parameters (D, D*, f, fD*) of T1-stage NPC tumors and nasopharyngeal mucosa of healthy control. The mean BF and D* of T1-stage NPC were higher than those of healthy control. And the BF correlated positively with D* and fD*. Therefore, ASL and IVIM could reflect blood perfusion difference between T1-stage NPC and benign nasopharyngeal mucosa, which is potential to help the early diagnosis of NPC.

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