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Abstract #5403

Low Apparent Diffusion Coefficient Value Predicts Early Progression of Skull Base Meningiomas

Ching Chung Ko1, Sher Wei Lim2, Tai Yuan Chen1, Jeon Hor Chen3,4, Chien Feng Li5, and Yow Ling Shiue6

1Medical Imaging, Chi Mei Medical Center, Tainan, Taiwan, 2Neurosurgery, Chi Mei Medical Center, Chiali, Tainan, Taiwan, 3Radiology, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan, 4Center for Functional Onco-Imaging, University of California Irvine, Irvine, CA, United States, 5Pathology, Chi Mei Medical Center, Tainan, Taiwan, 6Institute of Biomedical Science, National Sun Yat-Sen University, Kaohsiung, Taiwan

A recent study described the extent of tumor resection and ADC values could offer better prediction of progression/recurrence (P/R) in meningiomas than histopathological grading. Although complete resection of tumor is a key determining factor of recurrence in meningiomas, it is often difficulty to achieve for the skull base meningiomas (SBM) due to complex neurovascular structures. In this study, we investigated the preoperative CT and MR imaging features for the prediction of early P/R in SBM, with emphasis on ADC values. Our results found that low ADC value and adjacent bone invasion could predict high risk of early P/R in SBM, and therefore, offer clinically vital information for the planning of treatment.

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