Abstract #5409

Evaluation of a new semi-automatic delineation method for quantitative analysis of tumors: application to head and neck squamous cell carcinoma

Kanae Moriyama¹, Hiroyuki Sugimori², Noriyuki Fujima³, and Toru Yamamoto²

¹Graduate school of Health Science, Hokkaido University, Sapporo, Japan, ²Faculty of Health Science, Hokkaido University, Sapporo, Japan, ³Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan

Objective determination of tumor region of interest (ROI) on MR images is expected for quantitative analysis of tumors. We developed a semi-automatic method of ROI delineation. We applied this method to head and neck squamous cell carcinoma and evaluated the matching of the ROI delineation by our method and an experienced radiologist. The ADC values were compared for different ROI delineation methods. Averagely, 80% of the area of the ROI matched and the difference of the ADC value was within 2% (sd), showing that our new method of tumor delineation can be used to analyze the tumor characteristics quantitatively.

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