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Abstract #5410

Correlation of tumor blood flow in head and neck squamous cell carcinoma by pseudo-continuous arterial spin labeling with parameters of dynamic contrast-enhanced MRI

Young Jun Choi1, Jeong Hyun Lee1, and Josef Pfeuffer2

1Asan Medical Center, Seoul, Republic of Korea, 2Siemens healthcare, MR Application development, Erlangen, Germany

The aim of this prospective study was to evaluate the correlation between tumor blood flow (TBF) measurement using pseudo-continuous arterial spin labeling (pCASL) and parameters of DCE-MRI in patients with head and neck squamous cell carcinoma (HNSCC). We scanned 26 patients with HNSCC using 3T MRI with both pCASL and DCE-MRI. There were significant correlation between TBF of pCASL and wash-in, signal enhancement ratio, and Vp of DCE-MRI, with a correlation coefficient of 0.649, 0.642, and 0.507, respectively (P<0.01). The pCASL can be a useful tool for noninvasive assessments of the TBF in patients with HNSCC.

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