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Abstract #5411

Texture analysis applied to MRI of nerves affected with chronic inflammatory demyelinating neuropathy.

Paolo F Felisaz1, Andrea Poli1, Giovanni Vitale1, Raimondo Vitale1, Laura Piccolo2, Andrea Cortese2, Niels Bergsland3, Anna Pichiecchio3, and Stefano Bastianello3,4

1Radiology, University of Pavia, Pavia, Italy, 2Neurology Department, C. Mondino National Neurological Institute, Pavia, Italy, 3Neuroradiological Department, C. Mondino National Neurological Institute, Pavia, Italy, 4Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy

Introduction. Texture analysis was applied to MR images of peripheral nerves obtained with MR micro-neurography. Materials and Methods. Ankle tibial nerves were imaged at 3T in 10 patients affected with chronic inflammatory demyelinating neuropathy and 10 healthy subjects. Multiple subsets of textural features were compared, using different extraction methods and statistical analyses. The most discriminating features were selected and compared to the automatically extracted subsets. Results. Feature subset extracted from the whole pool of features performed better than the ones obtained by specific groups of features. Conclusion. Texture analysis may have a role in discriminating between pathologic and normal nerves.

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