Abstract #5411

Texture analysis applied to MRI of nerves affected with chronic inflammatory demyelinating neuropathy.

Paolo F Felisaz¹, Andrea Poli¹, Giovanni Vitale¹, Raimondo Vitale¹, Laura Piccolo², Andrea Cortese², Niels Bergsland³, Anna Pichiecchio³, and Stefano Bastianello^3,4

¹Radiology, University of Pavia, Pavia, Italy, ²Neurology Department, C. Mondino National Neurological Institute, Pavia, Italy, ³Neuroradiological Department, C. Mondino National Neurological Institute, Pavia, Italy, ⁴Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy

Introduction. Texture analysis was applied to MR images of peripheral nerves obtained with MR micro-neurography. Materials and Methods. Ankle tibial nerves were imaged at 3T in 10 patients affected with chronic inflammatory demyelinating neuropathy and 10 healthy subjects. Multiple subsets of textural features were compared, using different extraction methods and statistical analyses. The most discriminating features were selected and compared to the automatically extracted subsets. Results. Feature subset extracted from the whole pool of features performed better than the ones obtained by specific groups of features. Conclusion. Texture analysis may have a role in discriminating between pathologic and normal nerves.

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