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Abstract #5459

Inter-site MRI scanner resolution and stability variance revealed by EPI fMRI phantom scans: a multi-site Canadian study

M. Aras Kayvanrad1, Aditi Chemparathy1, Stephen Arnott1, Fan Dong1, Mojdeh Zamyadi1, Tom Gee1, Robert Bartha2,3, Christopher Scott4, Sandra Black4, Sean Symons4, Glenda MacQueen5, Jacqueline Harris5, Andrew Davis6, Geoffrey Hall6, Stefanie Hassel5,7, and Stephen Strother1,8

1Rotman Research Institute, University of Toronto, Toronto, ON, Canada, 2Robarts Research Institute, Western University, London, ON, Canada, 3Medical Biophysics, Western University, London, ON, Canada, 4Sunnybrook Research Institute, Toronto, ON, Canada, 5The Mathis Centre for Mental Health Research and Education, University of Calgary, Calgary, AB, Canada, 6Department of Psychology, Behaviour and Neuroscience, McMaster University, Hamilton, ON, Canada, 7School of Life and Health Sciences, Aston University, Birmingham, United Kingdom, 8Medical Biophysics, University of Toronto, Toronto, ON, Canada

The Ontario Neurodegenerative Disease Research Initiative (ONDRI) and the Canadian Biomarker Integration Network in Depression (CAN-BIND) are multisite longitudinal studies that employ 12 MRI scanners across Canada (6 in CAN-BIND) to collect neuroimaging data. To ensure comparability of neuroimaging data collected at different sites, fBIRN (functional Biomedical Informatics Research Network) phantoms have been scanned approximately monthly at each site for more than two years to obtain quality assurance (QA) measures from the fBIRN pipeline. In this abstract we present our investigations into within- and between-site variations due primarily to differences in full-width-at-half-maximum (FWHM) measures of imaging resolution.

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