Meeting Banner
Abstract #5486

On the sensitivity of T1 mapping methods to myelin

Damien Nguyen1,2, Tobias Kober3,4,5, and Oliver Bieri1,2

1Radiological Physics, University Hospital Basel, Basel, Switzerland, 2Department of Biomedical Engineering, University of Basel, Basel, Switzerland, 3Advanced Clinical Imaging Technology (HC CMEA SUI DI BM PI), Siemens Healthineers, Lausanne, Switzerland, 4Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, 5LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

For homogeneous and isotropic probes, different MR relaxometry methods are expected to yield consistent results. For tissues, however, wide-spread T1 and T2 relaxation times are reported in the literature. Especially in the brain, we hypothesize that the microstructure, e.g. the presence of myelin, affects the apparent observed T1, as assessed by different imaging sequences. As a result, apparent differences in T1 might reflect valuable information on the underlying tissue microstructure, such as myelination.

This abstract and the presentation materials are available to members only; a login is required.

Join Here