Abstract #5499

In vivo high-field myelin water imaging: Investigating the T2 distribution at 7T

Vanessa Wiggermann^1,2,3, Alex L MacKay^1,2,4, Gunther Helms^5,6, and Alexander Rauscher^1,2,3,7

¹Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, ²UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada, ³Pediatrics, University of British Columbia, Vancouver, BC, Canada, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Swedish National 7T MRI Facility, Lund University, Lund, Sweden, ⁶Medical Radiation Physics, Lund University, Lund, Sweden, ⁷BC Children's Research Centre, University of British Columbia, Vancouver, BC, Canada

With the increased frequency of human 7T scanners, there is also a drive towards the implementation advanced MR sequences, such a myelin water imaging, at high fields. Here, we demonstrate the feasibility of translating 3T myelin acquisitions scheme, GRASE, to 7T. We studied the distribution of T₂ values at 7T and determined that myelin water has a T₂<25ms. We obtained excellent agreement for myelin water fraction values in the corpus callosum between 3T and 7T.

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