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Abstract #5500

robust principle component analysis (rPCA) in multi-echo gradient-echo imaging: application in visualizing myelin-related signal without exponential modeling.

Jaewook Shin1, Hongpyo Lee1, and Dong-Hyun Kim1

1Electrical and Electronic engineering, Yonsei University, Seoul, Republic of Korea

In white matter, it is possible to describe multi-echo gradient-echo (mGRE) signal as the summation of multiple exponential decays. However, fitting to this model is sensitive to the error in the raw mGRE signal. In this study, mGRE signal is decomposed to a low rank plus sparsity component using robust principle component analysis (rPCA). Through this, myelin-related signal was extracted without performing exponential modeling. The sparse signal showed myelin-like contrast similar to other mGRE based myelin water imaging.

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