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Abstract #5504

The developmental dependence of the contrast between white and grey matter in spinal cord: the effect of non-aqueous species content

Uzi Eliav1, Peter J. Basser2, Efrat Sasson1, and Gil Navon1

1School of Chemistry, Tel Aviv University, Tel Aviv, Israel, 2SQITS/NICHD, NIH, Bethesda, MD, United States

Recently an imaging pulse sequence based on selective saturation of the water that drives magnetization transfer from the non-aqueous semi-solid part of the tissues was introduced. This technique allows the estimation of the fraction of the protons in the non-aqueous species. It separates the exchange processes from T1 in a simple way. In the current study, using this technique, we demonstrate changes with age of the non-aqueous species content in porcine spinal cord.

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