The purpose of this study was to investigate the feasibility and utility of isotropic perfusion maps obtained using multi-band (MB) single-shot echo-planar imaging (EPI) technique. We evaluated the quantitative equivalence between MB dynamic susceptibility contrast-enhanced (DSC) magnetic resonance imaging (MRI) and single-band (SB) DSC MRI, as well as the superiority of registration accuracy in isotropic MB-DSC MRI compared with anisotropic SB-DSC MRI. MB-DSC MRI yields isotropic perfusion maps that can improve the registration accuracy and multisection assessment by creating multiplane reconstruction, without deteriorating or altering the quantitative parameters.
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