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Abstract #5515

Slice-Accelerated Gradient-Echo Echo-Planar Imaging: Feasibility and Utility of Isotropic Perfusion Imaging

Yasuaki Tsurushima1, Ryuji Nojiri1, Takahiro Mihara1, Keiichi Ishigame1, Tomohiro Takamura2, and Masaaki Hori2

1Radiology, Tokyo Medical Clinic, Tokyo, Japan, 2Radiology, Juntendo University School of Medicine, Tokyo, Japan

The purpose of this study was to investigate the feasibility and utility of isotropic perfusion maps obtained using multi-band (MB) single-shot echo-planar imaging (EPI) technique. We evaluated the quantitative equivalence between MB dynamic susceptibility contrast-enhanced (DSC) magnetic resonance imaging (MRI) and single-band (SB) DSC MRI, as well as the superiority of registration accuracy in isotropic MB-DSC MRI compared with anisotropic SB-DSC MRI. MB-DSC MRI yields isotropic perfusion maps that can improve the registration accuracy and multisection assessment by creating multiplane reconstruction, without deteriorating or altering the quantitative parameters.

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