Absolute CBF quantification using ASL requires the normalization of the magnetization difference images by the equilibrium magnetization of arterial blood, which is usually extrapolated from the equilibrium magnetization measured in tissue. Although different calibration methods have been previously compared, a number of subtle processing options made in their practical implementation are often assumed or overlooked, compromising the utility of absolute quantification. We systematically compared different calibration methods and associated options in multiple post-labeling-delay pulsed ASL and found that they can severely impact CBF quantification. Our results highlight the need for consistent calibration pipelines for CBF quantification using ASL.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords