Meeting Banner
Abstract #5557

Resting-State Functional Connectivity of Subcortical Grey Matter Correlates with Fatigue in Young Adults with Multiple Sclerosis

Andrew LaBella1, Lauren Krupp2, Leigh Charvet2, Lev Bangiyev3, and Tim Q Duong3

1Biomedical Engineering, Stony Brook University, Stony Brook, NY, United States, 2Multiple Sclerosis Comprehensive Care Center, NYU, New York, NY, United States, 3Radiology, Stony Brook University, Stony Brook, NY, United States

While striatal and thalamic networks have been linked with fatigue in MS, they haven’t been explored in any young adult MS population. Further probing is needed to fully understand the fatigue correlate in MS and how it compares with differences between healthy controls and MS patients. In this study, we compared resting state functional connectivity measures in healthy controls, fatigued, and non-fatigued MS patients. Our results demonstrate that fatigue correlates with deficits in subcortical connectivity with several resting state networks. We found overlap between certain MS-related and fatigue-related changes, providing further insight into MS pathology and its fatigue correlate.

This abstract and the presentation materials are available to members only; a login is required.

Join Here