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Abstract #5560

Dynamic development of spontaneous neuronal activity in postpartum women: A longitudinal resting-state functional MRI study

Kaihua Zhang1,2, Mengxing Wang2, Jilei Zhang2, Haifeng Lu2, Zhong Chen*1, and Xiaoxia Du*2

1Department of Electronic Science, Xiamen University, Xiamen, China, 2Shanghai Key Laboratory of Magnetic Resonance and Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China

Investigating the neuroanatomical and functional bases in postpartum women have contributed to understanding the processing of cognitive and emotional alterations. The objective of this study was to examine spontaneous neuronal activity and functional connectivity of resting-state networks in postpartum women using a longitudinal resting-state functional magnetic resonance imaging. Twenty-three postpartum women were recruited. Amplitude of low-frequency fluctuation (ALFF), regional homogeneity (ReHo) and functional connectivity were calculated to measure spontaneous neuronal activity and brain network. Results revealed that changes in resting state brain network might be dynamic development for adaptive changes including cognitive function and empathic processing in postpartum women.

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