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Abstract #5574

Semantic verbal memory outcome in TLE and ETLE patients after surgery using fMRI

Kapil Chaudhary1, Senthil Kumaran2, P Sarat Chandra3, Ashima Nehra4, and Manjari Tripathi1

1Neurology, AIIMS, New Delhi, India, 2NMR, AIIMS, New Delhi, India, 3Neurosurgery, AIIMS, New Delhi, India, 4Neuropsychology, AIIMS, New Delhi, India

Memory can be broadly classified as sensory (process > 1 second), short term (>1 minute) and long term encoding in which information is encoded, stored, and retrieved. The surgical planning in drug refractory epilepsy (DRE) patients is usually associated with memory deficits. We measured BOLD activation during semantic verbal memory task using auditory stimulus and correlation with clinical parameters in patients (pre and 6 month of post-surgery) and controls. Study revealed anterior temporal lobe resection (ATLR) including removal of medial structures surrounding anterior temporal lobe may develop memory deficits in left TLE patients.

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