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Abstract #5604

Improve PCASL Brain Imaging at 7T Using Dynamically Applied B1+ Shimming Solutions

Xiufeng Li1, Dingxin Wang1, Xiaoping Wu1, Pierre-Francois Van de Moortele1, Kamil Ugurbil1, and Gregory J. Metzger1

1Center for Magnetic Resonance Research, School of Medicine, University of Minnesota, Minneapolis, MN, United States

The rapid decline of transmit B1 ( B1+) toward the inferior brain regions and large B1+ inhomogeneity across blood feeding arteries at the labeling plane impose great challenges for high quality pseudo-continuous arterial spin labeling (PCASL) brain imaging at 7T. Recent studies at 7T have suggested that dynamically applied B1+ shimming solutions separately targeted to imaging and labeling regions can help to overcome these challenges. We implemented and evaluated the dynamic B1+ shimming approach for PCASL brain imaging at 7T, demonstrating that such an approach can greatly improve B1+ performance for blood tagging.

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