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Abstract #5605

Characterize the relaxation effect during the adiabatic radiofrequency (RF) pulses on relaxation model for continuous wave constant amplitude spin-lock

Weitian Chen1 and Baiyan Jiang1

1Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong

Adiabatic RF pulses can be used for simultaneous compensation of B1 RF and B0 field inhomogeneity during continuous wave constant amplitude spin-lock. However, due to a relatively long duration of the adiabatic RF pulses, the relaxation effect during the adiabatic RF pulses can introduce a non-negligible effect on the conventional mono-exponential model used to describe T1rho relaxation during the spin-lock. Consequently, quantification using the conventional model can introduce errors. Based on Bloch equations, we derived that such relaxation effect contributes a DC component to the conventional mono-exponential model. We used simulation and in vivo MRI scan to demonstrate our theory.

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