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Abstract #5606

Validation of Fat Quantitation in Human Liver using SSGR technique

Meining Chen1, Hai Luo1, Beck Zhu1, Richard Chou1, Chao Wang1, Xia Liu1, Wei Bian1, and Ziyue Wu1,2

1Alltech Medical Systems, Chengdu, China, 2Alltech Medical System America, Solon, OH, United States

MRI has become the mainstay for noninvasive fat quantification in liver in routine clinical practice. To quantify fat fraction, the Dixon method is used most often. However, it is associated with a nontrivial image reconstruction process. In this study, we aim to perform fat quantification using the slice-selective gradient reversal (SSGR) technique, which was proposed previously but has not been validated in human liver. Our evaluation shows that the technique can efficiently separate water and fat, quantifying fat fraction that is highly correlated with that using the Dixon method.

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