Meeting Banner
Abstract #5607

Comparison of two alternative sequences for human in-vivo brain MR Current Density Imaging (MRCDI)

Cihan Göksu1,2, Lars G. Hanson1,2, Hartwig R. Siebner2,3, Philipp Ehses4,5, Klaus Scheffler4,6, and Axel Thielscher1,2

1Center for Magnetic Resonance, DTU Elektro, Technical University of Denmark, Kgs. Lyngby, Denmark, 2Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark, 3Department of Neurology, Copenhagen University Hospital, Bispebjerg, Denmark, 4High-Field Magnetic Resonance Center, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany, 5German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 6Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

MRCDI is a novel technique, utilizing different phase-sensitive MR methods for non-invasive measurements of weak currents in the human body, which is important in several neuroscience applications. Here, we compare the in-vivo performance of two different MR methods, multi-echo spin echo (MESE) and steady-state free precession free induction decay (SSFP-FID), with single- vs. multi-gradient-echo readouts. We demonstrate that multi-gradient-echo readouts improve both methods. We validate the linear dependence of the measured current-induced magnetic field on the injected current strength for both methods, and propose the more efficient SSFP-FID method as being well suited for highly sensitive single-slice human in-vivo MRCDI.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords