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Abstract #5622

Accuracy of 2D APT imaging with short acquisition time based on a self B0 correction using the TSE-Dixon method

Chiaki Tokunaga1, Tatsuhiro Wada1, Osamu Togao2, Yasuo Yamashita1, Kouji Kobayashi1, and Yoshiyuki Umezu1

1Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan, 2Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

The purpose of our study was to investigate the accuracy of amide proton transfer (APT) imaging using the Dixon method. Five samples were prepared from egg white albumin at the different concentration diluted with phosphate buffer solution. We measured APT signal intensities of the phantoms using the conventional method with separate B0 map and the TSE-Dixon method. No statistical significant differences were found among the APT weighted signals measured with the two different acquisition methods at each concentration. The TSE-Dixon method enabled shorter acquisition time and had an equivalent quantitative accuracy compared to the conventional method with separate B0 mapping.

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