Abstract #5626

T1 mapping based on Look-Locker and variable-flip-angle techniques: comparison in phantom measurements and in a patient collective

Claudia Fellner¹, Stefanie Pölsterl¹, Niklas Verloh¹, Dominik Nickel², Stephan Kannengießer², Philipp Wiggermann¹, Christian Stroszczynski¹, and Michael Haimerl¹

¹Institute of Radiology, University Hospital Regensburg, Regensburg, Germany, ²MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Two methods for T1 mapping – 2D Look-Locker (LL) and 3D variable-flip-angle (VFA) combined with a 2-point-Dixon technique – were compared in phantom and patient measurements. LL yielded reliable results with homogeneous T1 maps of the liver, but was restricted to 3 slices. VFA yielded T1 mapping of the whole liver, but the homogeneity of T1 values across the liver was reduced which led to marked reduction of mean T1 in some patients compared with LL. The VFA variants based on in-phase and water signals showed differences in T1 for increased hepatic fat.

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