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Abstract #5626

T1 mapping based on Look-Locker and variable-flip-angle techniques: comparison in phantom measurements and in a patient collective

Claudia Fellner1, Stefanie Pölsterl1, Niklas Verloh1, Dominik Nickel2, Stephan Kannengießer2, Philipp Wiggermann1, Christian Stroszczynski1, and Michael Haimerl1

1Institute of Radiology, University Hospital Regensburg, Regensburg, Germany, 2MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Two methods for T1 mapping – 2D Look-Locker (LL) and 3D variable-flip-angle (VFA) combined with a 2-point-Dixon technique – were compared in phantom and patient measurements. LL yielded reliable results with homogeneous T1 maps of the liver, but was restricted to 3 slices. VFA yielded T1 mapping of the whole liver, but the homogeneity of T1 values across the liver was reduced which led to marked reduction of mean T1 in some patients compared with LL. The VFA variants based on in-phase and water signals showed differences in T1 for increased hepatic fat.

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