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Abstract #5627

3D isotropic multi-parameter mapping and synthetic imaging of the brain with 3D-QALAS: comparison with 2D MAGIC

Ken-Pin Hwang1, Suchandrima Banerjee2, Tao Zhang3, and Marcel Warntjes4

1Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States, 2MR Applications and Workflow, GE Healthcare, Menlo Park, CA, United States, 3MR Applications and Workflow, GE Healthcare, Waukesha, WI, United States, 4SyntheticMR, Linkoping, Sweden

3D QALAS is a promising new technique that simultaneously maps T1, T2, and PD in a single 3D acquisition. Both 3D QALAS and 2D MAGIC were applied for synthetic imaging and quantification in human brains. While T1 and T2 values were comparable between the two techniques, 3D QALAS was simpler to process and achieved smaller voxel sizes over larger matrices with similar acquisition times, resulting in less partial volume effects. 2D MAGIC maintained the high in-plane resolution and efficiency of an interleaved multi-slice technique. 3D QALAS thus presents an attractive quantification method for therapy planning and tissue volume measurement applications.

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