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Abstract #5643

Simultaneous T1 and T2 parametric mapping and synthetic MRI with IR-prepared echo-split gradient-echo and spin-echo imaging and parametric POCSMUSE reconstruction

Mei-Lan Chu1,2 and Nan-kuei Chen2

1Department of Biomedical Sciences and Engineering, National Central University, Taoyaun, Taiwan, 2Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States

Our novel simultaneous T1 and T2 mapping framework, integrating IR-prepared echo-split GRASE acquisition and parametric POCSMUSE reconstruction, has the following advantages. First, T1 and T2 maps can be derived from four sets of single-shot IR-prepared echo-split GRASE data, with very high scan efficiency. Second, T1 and T2 relaxation time constants can be accurately measured by the parametric POCSMUSE algorithm, which models multiplexed signals across CPMG echoes and multiple IR-prepared data of multi-echo-pathway. Third, synthetic multi-contrast images can be generated from the measured parametric maps.

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