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Abstract #5644

Improved quantification of cerebral blood flow in gray matter and white matter using non-Fourier based reconstruction

Phil Lee1,2, Peter Adany2, and In-Young Choi1,2,3

1Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, United States, 2Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, United States, 3Neurology, University of Kansas Medical Center, Kansas City, KS, United States

Accurate quantification of CBF in GM and WM is challenging due to intrinsically low SNR and low spatial resolution of CBF maps. In this study we propose a new approach in quantifying CBF in GM and WM, based on spectral localization by imaging (SLIM), which provides accurate CBF values in compartments with complex shapes, e.g., GM and WM by incorporating high-resolution anatomical information into CBF reconstruction at reduced scan time.

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