Meeting Banner
Abstract #0045

Investigating the effects of an early intervention in preterm newborns: A resting-state functional connectivity study

Serafeim Loukas1,2, Djalel E Meskaldji1,3, Lara Lordier1, Joana Sa de Almeida1, Dimitri Van De Ville2, and Petra S Huppi1

1Division of Development and Growth, Department of Pediatrics, University of Geneva, Geneva, Switzerland, 2Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland, 3Institute of Mathematics, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland

In this study we explore the effects of an early intervention on functional connectivity in preterm newborns. A group of preterm newborns underwent musical intervention in NICU during hospitalization. At TEA, two resting-state fMRI runs were collected. The first was before and the second after the presentation of the same musical stimulus used for the early intervention. We construct the functional connectomes using Accordance and we employ connectome-based statistical methods to unveil changes in functional connectivity evoked by this familiar musical stimulus. Increased connectivity is observed in key brain areas involved in music and emotion processing supporting previous findings.

This abstract and the presentation materials are available to members only; a login is required.

Join Here