Meeting Banner
Abstract #0065

Combined Diffusion-Relaxometry MRI to Identify Dysfunction in the Human Placenta

Paddy J. Slator1, Jana Hutter2,3, Marco Palombo1, Laurence H. Jackson2,3, Eleftheria Panagiotaki1, Alison Ho4, Lucy C. Chappell4, Mary A. Rutherford3, Joseph V. Hajnal2,3, and Daniel C. Alexander1

1Centre for Medical Image Computing, University College London, London, United Kingdom, 2Biomedical Engineering, Kings College London, London, United Kingdom, 3Centre for the Developing Brain, King's College London, London, United Kingdom, 4Women's Health Department, King's College London, London, United Kingdom

We demonstrate simultaneous diffusion-relaxometry in the in-vivo human placenta. Two MRI measures widely used for characterizing the placenta, T2* relaxometry and diffusion, are combined into a single scan. We estimate the T2*-ADC spectrum, which enables study of the coupling between these complementary MR contrasts by disentangling joint effects. This gives new potential for improved characterisation of placental dysfunction compared to single contrast MRI and/or ultrasound, and hence could inform improved evaluation of pregnancy complications.

This abstract and the presentation materials are available to members only; a login is required.

Join Here