Abstract #0065

Combined Diffusion-Relaxometry MRI to Identify Dysfunction in the Human Placenta

Paddy J. Slator¹, Jana Hutter^2,3, Marco Palombo¹, Laurence H. Jackson^2,3, Eleftheria Panagiotaki¹, Alison Ho⁴, Lucy C. Chappell⁴, Mary A. Rutherford³, Joseph V. Hajnal^2,3, and Daniel C. Alexander¹

¹Centre for Medical Image Computing, University College London, London, United Kingdom, ²Biomedical Engineering, Kings College London, London, United Kingdom, ³Centre for the Developing Brain, King's College London, London, United Kingdom, ⁴Women's Health Department, King's College London, London, United Kingdom

We demonstrate simultaneous diffusion-relaxometry in the in-vivo human placenta. Two MRI measures widely used for characterizing the placenta, T2* relaxometry and diffusion, are combined into a single scan. We estimate the T2*-ADC spectrum, which enables study of the coupling between these complementary MR contrasts by disentangling joint effects. This gives new potential for improved characterisation of placental dysfunction compared to single contrast MRI and/or ultrasound, and hence could inform improved evaluation of pregnancy complications.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.