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Abstract #0109

Prediction of Peripheral Nerve Stimulation Thresholds of MRI Gradient Coils using Coupled Electromagnetic and Neurodynamic Simulations

Mathias Davids1,2, Bastien Guérin2,3, Axel vom Endt4, Lothar R. Schad1, and Lawrence L. Wald2,3,5

1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, 2Dept. of Radiology, A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Harvard Medical School, Boston, MA, United States, 4Siemens Healthcare, Erlangen, Germany, 5Harvard-MIT Division of Health Sciences Technology, Cambridge, MA, United States

Peripheral Nerve Stimulation (PNS) has become the major limitation in many fast MRI sequences for state-of-the-art gradient systems. We present the first (to our knowledge) full PNS model for assessing magnetostimulation thresholds and a method to incorporate these thresholds as constraints in the coil-winding design phase. Our model consists of comprehensive female and male body models for EM simulations, co-registered atlases of peripheral nerves, and a neurodynamic model describing the nerve responses to induced electric fields. We validated our framework based on three commercial MR gradient systems and found close resemblance between simulated thresholds and experimentally obtained group PNS thresholds.

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