Abstract #0111

Echo Planar Time-resolved Imaging (EPTI)

Fuyixue Wang^1,2, Zijing Dong^1,3, Timothy G. Reese¹, Berkin Bilgic^1,4, Mary Katherine Manhard¹, Jingyuan Chen¹, Jonathan R. Polimeni^1,2,4, Lawrence L. Wald^1,2,4, and Kawin Setsompop^1,2,4

¹Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ²Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, ³Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, ⁴Department of Radiology, Harvard Medical School, Boston, MA, United States

A new technique, termed Echo Planar Time-resolved Imaging (EPTI), was developed to address EPI’s geometric distortion and blurring, and to provide temporal signal evolution information across the EPI readout window. Using a small number of EPTI-shots, a time-series of multi-contrast images can be created free of distortion and blurring (up to 100 T₂- and T₂*-weighted images). This should make EPTI useful for numerous applications. Here, we demonstrated EPTI in brain to provide i) rapid simultaneous quantitative mapping of T₂, T₂*, proton density and tissue phase, as well as ii) multi-echo and quantitative T₂* fMRI.

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