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Abstract #0139

Pilot study on facioscapulohumeral muscular dystrophy patients with dynamic phase contrast imaging of electrically stimulated quadriceps muscles

Xeni Deligianni1,2, Francesco Santini1,2, Giorgio Tasca3, Mauro Monforte3, Francesca Solazzo4, Raimondo Vitale5, Paolo Felisaz6, Giancarlo Germani4, Niels Bergsland4, Enzo Ricci3, and Anna Pichiecchio4

1Department of Radiology/Division of Radiological Physics, University Hospital Basel, Basel, Switzerland, 2Department of Biomedical Engineering, University of Basel, Basel, Switzerland, 3Unità Operativa Complessa di Neurologia, Dipartimento di Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 4Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy, 5University of Pavia, Pavia, Switzerland, 6Radiology Department, Desio Hospital ASST, Monza, Italy

Facioscapulohumeral muscular dystrophy is characterized by a peculiar non-linear muscle-by-muscle involvement and is very hard to predict. The purpose of this study was to use dynamic phase contrast MR imaging of electrically stimulated quadriceps muscle to characterize the elastic potential of the muscle in FSHD patients and contribute to the understanding of this challenging disease. Velocity, strain, and strain rate were analyzed and compared to the results of physical examination.

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