While diffusion MRI tractography has provided important insights on the human brain connectome, fibre-tracking through heterogeneous voxels has proven to be a challenging endeavour. Recently, we devised MRI acquisition- and processing methods to resolve sub-voxel heterogeneity with nonparametric 5D relaxation-diffusion distributions where contributions from distinct tissues are separated while circumventing the use of limiting assumptions. The separation between tissue-signals provides a clean mapping of nerve fibres that can then be used as an input in fibre-tracking algorithms. Additionally, values of relaxation rates and diffusivities are estimated for each distinct fibre bundle, potentially giving tract-specific information on chemical composition and microstructure.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords