Fiber orientation distributions (FODs) of white matter (WM) are commonly estimated from brain diffusion MRI data with spherical deconvolution (SD) approaches. Typically, only WM is considered to be anisotropic in SD, relying on suboptimal isotropic modeling of grey matter (GM). Here we present a general framework to reconstruct multiple anisotropic FODs (mFODs) from multiple response functions, allowing for the investigation of anisotropy in GM. The estimated mFODs were evaluated on a dataset from the HCP project with five response functions generated with the diffusion kurtosis and NODDI approaches, and their performances compared to state-of-the-art SD approaches.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords