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Abstract #0232

Improved gSlider Reconstruction for Isotropic High-Resolution DTI Using A Model-Based Method and Virtual Coil Concept

Simin Liu1, Erpeng Dai1,2, Zijing Dong1,3,4, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Department of Radiology, Stanford University, Stanford, CA, United States, 3A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, 4Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States

Recently, generalized SLIce Dithered Enhanced Resolution (gSlider) has been proposed as a new acquisition strategy for isotropic high-resolution DTI. In this study, to further boost the SNR performance and reconstruction accuracy, the model-based DTI reconstruction method was merged into the gSlider reconstruction procedure. Moreover, virtual coil (VC) concept was also integrated into the proposed method to further improve the SNR of gSlider reconstruction. Compared with conventional GRAPPA, the superiority of the model-based method has been demonstrated by in vivo results, especially when in combination with the virtual coil concept.

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