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Abstract #0233

SMS-MUSSELS: A Navigator-free Reconstruction for Slice-accelerated Multi-shot Diffusion Imaging

Merry Mani1, Mathews Jacob1, Graeme McKinnon2, Baolian Yang2, Brian Rutt3, Adam Kerr3, and Vincent Magnotta1

1University of Iowa, Iowa City, IA, United States, 2GE Healthcare, Milwaukee, WI, United States, 3Stanford University, Stanford, CA, United States

Multi-shot diffusion-weighted (msDW) imaging schemes can improve the spatial resolution of DWIs. However, the multi-shot readout spans multiple TRs which reduce the time efficiency of msDWI. Hence the practical utility of multi-shot methods for high angular resolution imaging for fiber tracking purposes currently remains limited. To improve the time efficiency of msDWI, SMS acceleration can be employed. However, the DWIs from SMS-accelerated msDW acquisition will exhibit severe artifacts due to slice aliasing and inter-shot phase inconsistencies arising from the msDW encoding. We present a novel navigator-free reconstruction method to simultaneously slice unfold and jointly recover multi-shot diffusion data from an SMS-accelerated msDW acquisition. The method is shown to effectively reconstruct 4-shot DW data accelerated at a multi-band factor of 3.

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